They say at 25 the male brain becomes fully developed. Things become a lot more clear and you seem to understand more. They don't talk about the overwhelming sense of uncertainty, fear, and doubt that comes along with it though.
Traumas, bad habits, flaws, and powers are revealed to your mind in a way you have never been able to comprehend. 25-26 feels like starting a new game +. The knowledge from your previous experiences is all there and you're given the chance to face encounters without setting everything up in flames.